產(chǎn)品目錄

規(guī)格	500μg 1mg
CAS	1225382-70-6
別名	N/A
化學(xué)名	N/A
分子式	C32H37D7O7
分子量	547.7
溶解度	Chloroform: slightly soluble,Methanol: slightly soluble
儲存條件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Ciclesonide-d7 is intended for use as an internal standard for the quantification of ciclesonide by GC- or LC-MS. Ciclesonide is a prodrug form of the glucocorticoid receptor agonist desisobutyryl-CIC (des-CIC).1 CIC binds to the glucocorticoid receptor with a Ki value of 37 nM.2 It is selective for the glucocorticoid receptor over the estrogen, progesterone, and testosterone receptors. CIC inhibits eosinophil influx into the lung (ED50 = 0.49 mg/kg) and reduces sephadex-induced lung edema (ED50 = 0.72 mg/kg) in a rat model of ovalbumin-sensitized and -challenged airway inflammation. Formulations containing CIC have been used in the maintenance treatment of asthma and in the treatment of allergic rhinitis.

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原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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