13585831301
021-59541103 021-60443211
3004967995
13585831301021-59541103 021-604432113004967995
聯系人:高小姐
電話:021-59541103 021-60443211
手機:13585831301
Q Q： 3004967995
Email:3004967995@qq.com
詳細地址：上海嘉定區嘉羅公路1661
化學性質：
| 規格 | 5mg 10mg 25mg 50mg |
| CAS | 502-65-8 |
| 別名 | N/A |
| 化學名 | (6E,8E,10E,12E,14E,16E,18E,20E,22E,24E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene |
| 分子式 | C40H56 |
| 分子量 | 536.89 |
| 溶解度 | <3.24 mg/mL in DMSO, <2.94 mg/mL in EtOH, <3.3 mg/mL in H2O |
| 儲存條件 | Store at -20°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
產品描述：
Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.
Sufficient uptake of lycopene from the diet is necessary to benefit from its health promoting effects, since humans are unable to synthesise lycopene de novo. Lycopene significantly inhibits prostate and breast cancer cell growth at physiologically relevant concentrations of 1.25 μM and also causes a 30-40 % reduction in inhibitor of kappa B phosphorylation in the cells[1]. Increased intake of lycopene, a major carotenoid in tomatoes, consumed as the all-trans-isomer attenuates alcohol induced apoptosis in 2E1 cells and reduces risk of prostate, lung and digestive cancers. Lycopene plays a role in the protection against photooxidative processes by acting as singlet molecular oxygen and peroxyl radicals scavengers and can interact synergistically with other antioxidants[2]. Lycopene as a carotenoid can react with types of reactive oxygen species (ROS) in three different mechanisms: I) by electron-transfer, II) by hydrogen atom transfer or III) by adduct formation. Lycopene is able to deactivate singlet oxygen mainly by physical quenching[3]. Lycopene decreases ROS production in SK-Hep-1 cells through inhibition of NADPH oxidase, brought about in the PKC pathway[5].
Lycopene is the most predominant carotenoid in human plasma and has a half life of about 2-3 days[2]. Lycopene or processed tomatoes may lead to a reduction of intima-media thickness in vessel walls[3]. Lycopene exerts protective effects against ATZ-induced toxicity in rat adrenal cortex. These effects may be attributed to the antioxidative property of lycopene and its ability to activate the Nrf2/HO-1 pathway[4]. Lycopene improves hepatotoxicity acting as an antioxidant, reduces GSSG and regulates tGSH and CAT levels, reduces oxidative damage[5].
特別提醒：
1. 本產品僅供科研使用。請勿用于醫藥、臨床診斷或治療，食品及化妝品等用途。請勿存放于普通住宅區。
2. 為了您的安全和健康，請穿好實驗服并佩戴一次性手套和口罩操作。
原創作者：上海莼試生物技術有限公司
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普票匯款信息
賬 戶 名：上海生物
開 戶 行：中國銀行山東省分行營業部
賬 號：2169 2341 6278
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