產(chǎn)品目錄

規(guī)格	1mg 5mg
CAS	28115-68-6
別名	N/A
化學(xué)名	N/A
分子式	C20H20O6
分子量	356.4
溶解度	DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble
儲存條件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Pluviatolide is a lignan that has been found in B. chinense and has diverse biological activities, including antioxidant, enzyme inhibitory, and antispasmodic properties.1,2,3 It scavenges ABTS and 2,2-diphenyl-1-picrylhydrazyl radicals in cell-free assays (IC50s = 23.2 and 88.5 μM, respectively).1 Pluviatolide inhibits matrix metalloproteinase-7 (MMP-7) with an IC50 value of 260 μM.2 It decreases contractions induced by acetylcholine in isolated guinea pig ileum when used at concentrations of 30 and 100 μM.3

|1. Li, D.-Q., Wang, D., Zhou, L., et al. Antioxidant and cytotoxic lignans from the roots of Bupleurum chinense. J. Asian Nat. Prod. Res. 19(5), 519-527 (2017).|2. Muta, Y., Oyama, S., Umezawa, T., et al. Inhibitory effects of lignans on the activity of human matrix metalloproteinase 7 (matrilysin). J. Agric. Food Chem. 52(19), 5888-5894 (2004).|3. Zhang, G., Shimokawa, S., Mochizuki, M., et al. Chemical constituents of Aristolochia constricta: Antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid. J. Nat. Prod. 71(7), 1167-1172 (2008).

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1. 本產(chǎn)品僅供科研使用。請勿用于醫(yī)藥、臨床診斷或治療，食品及化妝品等用途。請勿存放于普通住宅區(qū)。

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原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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