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化學性質:
規格 | 10mM (in 1mL DMSO) 50mg |
CAS | 69-57-8 |
別名 |
|
化學名 | sodium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[ |
分子式 | C16H18N2O4S.Na |
分子量 | 356.37 |
溶解度 | ≥ 13.7mg/mL in DMSO |
儲存條件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
產品描述:
IC50: 0.002 μg/ml for Streptococcus pneumoniae serotype 4
Penicillin G sodium is a penicillin antibiotic against sensitive organisms during the stage of active multiplication and acts by inhibiting the biosynthesis of bacterial cell wall mucopeptides. It is not active against penicillinase-producing bacteria, which include many strains of staphylococci.
In vitro: Penicillin G sodium works by interfering with the formation of the bacteria's cell wall. This weakens the cell wall and kills the bacteria. Penicillin G is highly effective in-vitro against staphylococci, streptococci and pneumococci. Other organisms sensitive in-vitro to penicillin G are Neisseria gonorrhoeae, Bacillus anthracis, Corynebacterium diphtheriae, Clostridia et al. Treponema pallidum is extremely sensitive [1].
In vivo: With intermittent intramuscular administration of penicillin normal rats were cured after doses of 4 mg/kg/d, whereas decomplemented rats recovered only after daily doses of above 100 mg/kg. When penicillin was administered by way of continuous infusion, doses of 3.5 mg/kg/d were required for a cure of infections in both normal and decomplemented rats [2].
Clinical trials: Penicillin G sodium is used to treat a wide variety of bacterial infections. It is also used to prevent the heart infection in patients with certain heart diseases who are having surgery. Penicillin G sodium is known as a natural penicillin antibiotic. It works by stopping the growth of bacteria [1].
特別提醒:
1. 本產品僅供科研使用。請勿用于醫藥、臨床診斷或治療,食品及化妝品等用途。請勿存放于普通住宅區。
2. 為了您的安全和健康,請穿好實驗服并佩戴一次性手套和口罩操作。
原創作者:上海莼試生物技術有限公司
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