產(chǎn)品目錄

規(guī)格	10mM (in 1mL DMSO) 500mg 1g
CAS	59-14-3
別名	N/A
化學(xué)名	5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
分子式	C9H11BrN2O5
分子量	307.1
溶解度	≥ 15.35mg/mL in DMSO, ≥ 16.23 mg/mL in H2O with ultrasonic, ≥ 11.56 mg/mL in 0.9% NS with ultrasonic
儲(chǔ)存條件	4°C, protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

5-Bromodeoxyuridine (5-BrdU) is an analog of Thy that is incorporated into the DNA of cells undergoing the S-phase and can be detected by monoclonal antibodies or polyclona111.

In vitro: The effect of 5-BrdU on the proliferation was studied in the early phases of dedifferentiation of Nicotiana glauca pith explants grown. It was found to be wholly inhibitory only when given during the first 72 h of culture, this inhibition being reversed by simultaneous addition of either deoxyeytidine or thymidine [1].

In vivo: Young adult offspring mice were stained for 5-BrdU using a monoclonal antibody and the peroxidase-antiperoxidase method. The distribution of immunoreactive nuclei was very similar to the previous [3H]thymidine data. The pattern of labelled nuclei at different embryonic ages followed the spatiotemporal gradients described for cortical and hippocampal neurogenesis. These data indicate that BrdU can be used to map neuronal birthdates. [2].

Clinical trials: Currenlty no clinical data are available.

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原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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