產(chǎn)品目錄

規(guī)格	1 mg 5 mg 10 mg 25 mg
CAS	2141978-86-9
別名	N/A
化學(xué)名	N/A
分子式	C27H25BrN2O3
分子量	505.4
溶解度	DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
儲(chǔ)存條件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

K22 is an antiviral agent.1 It inhibits the replication of severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), human coronavirus 229E (HCoV-229E), feline coronavirus (FCoV), and mouse hepatitis virus (MHV) in Vero cells when used at a concentration of 40 µM. K22 inhibits the formation of double membrane vesicles, a hallmark of coronavirus replication, and inhibits viral RNA synthesis in HCoV-229E-infected MRC-5 cells. It also reduces viral titers in cells infected with various Arteriviridae or Torovirinae viruses.2

1.Lundin, A., Dijkman, R., BergstrÖm, T., et al.Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the Middle East respiratory syndrome virusPLoS Pathog.10(5)e1004166(2014) 2.Rappe, J.C.F., de Wilde, A., Di, H., et al.Antiviral activity of K22 against members of the order NidoviralesVirus Res.24628-34(2018)

特別提醒：

1. 本產(chǎn)品僅供科研使用。請勿用于醫(yī)藥、臨床診斷或治療，食品及化妝品等用途。請勿存放于普通住宅區(qū)。

2. 為了您的安全和健康，請穿好實(shí)驗(yàn)服并佩戴一次性手套和口罩操作。

原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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