產(chǎn)品目錄

規(guī)格	10mM (in 1mL DMSO) 10mg 25mg
CAS	42206-94-0
別名
化學(xué)名	(E)-5-(4-acetoxystyryl)-1,3-phenylene diacetate
分子式	C20H18O6
分子量	354.35
溶解度	≥ 13.85mg/mL in DMSO
儲存條件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Triacetyl Resveratrol is a cell-permeable and more stable resveratrol prodrug [1].

Triacetyl Resveratrol is a potential and cell-permeable resveratrol prodrug. In 32D-cl3 cells, triacetyl resveratrol (3', 5',4'-Tri-O-acetylresveratrol) protected cells from irradiation and increased radioresistance, and is slightly more potent than resveratrol [1]. In lysates derived from HEK293-TYR cells, triacetyl resveratrol inhibited human TYR activity with IC50 value of 20 μM. In HEMs, triacetyl resveratrol was less cytotoxic than resveratrol. In both murine melanoma B16/F10 cells and HEMs, triacetyl resveratrol effectively inhibited intracellular melanin contents increased by α-MSH and L-tyrosine, respectively. Triacetyl Resveratrol was easily digested to resveratrol by esterases [2]. In LNCaP cells, triacetyl-resveratrol activated p53, increased p21 and p53R2 and decreased PSA expression. In CWR22Rv1 cells (mutated p53), triacetyl-resveratrol induced G1/S arrest [3]. In MCF-7 and MDA-MB-231 breast cancer cells, triacetyl-resveratrol interacted avidly and specifically with integrin αvβ3 through binding at the site targeted by the RGD peptide. Triacetyl-resveratrol induced ERK and p38 phosphorylation [4].

特別提醒：

1. 本產(chǎn)品僅供科研使用。請勿用于醫(yī)藥、臨床診斷或治療，食品及化妝品等用途。請勿存放于普通住宅區(qū)。

2. 為了您的安全和健康，請穿好實驗服并佩戴一次性手套和口罩操作。

原創(chuàng)作者：上海莼試生物技術(shù)有限公司

在線咨詢

留言注意事項：

1.遵守中華人民共和國有關(guān)法律、法規(guī)，尊重網(wǎng)上道德，承擔一切因您的行為而直接或間接引起的法律責任。

2.請您真實的反映產(chǎn)品的情況,不要捏造、誣蔑、造謠。如對產(chǎn)品有任何疑問,也可以留言咨詢。

3.未經(jīng)本站同意，任何人不得利用本留言簿發(fā)布個人或團體的具有廣告性質(zhì)的信息或類似言論。

您感興趣的產(chǎn)品*
您的單位*
聯(lián)系人*
聯(lián)系電話*
詳細地址*
常用郵箱*
請輸入您對我們的意見或建議*
驗證碼*