產(chǎn)品目錄

規(guī)格	25μg 50μg 100μg
CAS	83851-42-7
別名	LTF4
化學名	5S-hydroxy-6R-(S-γ-glutamylcysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
分子式	C28H44N2O8S
分子量	568.7
溶解度	>50 mg/ml (per Ramki Iyer) in DMSO, >50 mg/ml (per Ramki Iyer) in DMF, >50 mg/ml (per Ramki Iyer) in Ethanol
儲存條件	Store at -80°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle. [1] The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4. [1] [2]

Reference:

[1]. Bernstrom, K., and Hammarstr?m, S. A novel leukotriene formed by transpeptidation of leukotriene E4. Biochemical and Biophysical Research Communications 109, 800-804 (1982).

[2]. Lord, A., Charleson, S., and Letts, L.G. Leukotriene F4 and the release of arachidonic acid metabolites from perfused guinea pig lungs in vitro. Prostaglandins 29, 651-660 (1985).

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原創(chuàng)作者：上海莼試生物技術有限公司

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