產(chǎn)品目錄

規(guī)格	1mg 5mg 10mg 25mg
CAS	216064-36-7
別名	Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu
化學(xué)名	β-Pompilidotoxin
分子式	C71H124N22O17
分子量	1557.9
溶解度	≥ 155.8mg/mL in DMSO
儲(chǔ)存條件	Desiccate at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

β-Pompilidotoxin, (C71H124N22O17), a peptide with the sequence H2N-Arg

-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu-amide, MW= 1557.88. Pompilidotoxin is a toxin from the venom of spider wasps that slows the inactivation of Na+channels. α-Pompilidotoxin (α-PMTX) can be extracted from the venom of a solitary wasp, Anopolis samariensis. β-Pompilidotoxin (β-PMTX) originates from the venom of another wasp, Batozonellus maculifrons(1). Homology α-PMTX has no structural homology with other toxins. It lacks disulfide bonds which are known to be present in other toxins acting on sodium channels, such as sea anemone toxins or scorpion toxins(2). Both α- and β-PMTX slow the inactivation of neuronal sodium channels (but not heart sodium channels), possibly by binding to the neurotoxin receptor site 3 on the extracellular surface of the sodium channel(3). β-PMTX has higher potency than α-PMTX. By slowing down the inactivation of sodium channels, PMTXs can potentiate synaptic transmission in the lobster neuromuscular endplate.

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1. 本產(chǎn)品僅供科研使用。請(qǐng)勿用于醫(yī)藥、臨床診斷或治療，食品及化妝品等用途。請(qǐng)勿存放于普通住宅區(qū)。

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原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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