產(chǎn)品目錄

規(guī)格	500mg 1g
CAS	N/A
別名	N/A
化學(xué)名	N/A
分子式	C20H37N3O13•XH2O
分子量	527.5
溶解度	DMSO: 3.3 mg/ml,PBS (pH 7.2): 3.3 mg/ml
儲存條件	-20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

產(chǎn)品描述：

Hygromycin B is an antibiotic which is used in molecular and cell biology to select for transformed cells expressing the hygromycin resistance gene.1,2 It is an aminoglycoside produced by the bacterium S. hygroscopicus which kills prokaryotic and eukaryotic cells by inhibiting protein synthesis.3,4 The hygromycin resistance gene (hyg or hph) encodes a phosphotransferase which inhibits hygromycin through phosphorylation.2

1.Kaster, K.R., Burgett, S.G., Rao, R.N., et al.Analysis of a bacterial hygromycin B resistance gene by transcriptional and translational fusions and by DNA sequencingNucleic Acids Research11(19)6895-6911(1983) 2.Blochlinger, K., and Diggelmann, H.Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eucaryotic cellsMolecular and Cellular Biology4(12)2929-2931(1984) 3.Eustice, D.C., and Wilhelm, J.M.Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesisAntimicrobial Agents and Chemotherapy26(1)53-60(1984) 4.CabaÑas, M.J., VÁzquez, D., and Modolell, J.Dual interference of hygromycin B with ribosomal translocation and with aminoacyl-tRNA recognitionEuropean Journal of Biochemistry8721-27(1978)

特別提醒：

1. 本產(chǎn)品僅供科研使用。請勿用于醫(yī)藥、臨床診斷或治療，食品及化妝品等用途。請勿存放于普通住宅區(qū)。

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原創(chuàng)作者：上海莼試生物技術(shù)有限公司

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